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Nobel Prize and drinking connection?

February 01, 2018

In 1998, the Nobel Prize for Medicine was awarded to three American scientists (Robert Furchgott, Louis Ignarro, and Ferid Murad) for identifying and documenting nitric oxide’s benefits in the human body.  Previously, in 1992 nitric oxide was proclaimed the “Molecule of the Year”  for its importance in neuroscience, physiology, and immunology.  Nitric oxide is a signaling molecule in many physiological and pathological processes, it also dilates blood vessels, raising blood supply and lowering blood pressure.

How effective is nitric oxide?  Well, for over 100 years, doctors used to prescribe nitroglycerin (a nitric oxide precursor) to relieve chest pain by causing the blood vessels supplying the heart muscle to relax which allowed oxygen-rich blood to nourish the heart.  Chemically, prescribed nitroglycerin was the same as the explosive… the pills are just in stable solid form (whew!).
 
Now it turns out that the icon behind the Nobel Prize, Alfred Nobel himself, made his fortune as the first to produce nitroglycerin on an industrial scale.  Scientists discovered that within the body, the enzyme mALDH converts nitroglycerin into nitric oxide.  And the nitric oxide is critical in relaxing and dilating blood vessels.

This opening up of blood vessels has a bonus effect of improving erections.  It’s no accident that popular erectile dysfunction drugs such as Viagra, Levitra, and Cialis work on nitric oxide pathways to increase blood flow.   Back in 2011, Durex even introduced a condom with a nitroglycerin based gel inside to enhance erections.  Can you see the tagline possibilities?  ‘Explosive sex!’  or just ‘Boom!’
 
Alright, let’s connect some more dots.  Power Defender contains the ingredient L-arginine, an amino acid that helps make proteins and plays a part in the removal of the toxin ammonia from the body. The interesting connection here is that in the body, arginine is also a nitric oxide precursor.  Meaning that in the body, arginine converts into …. Yep, nitric oxide!

OK, why all the fuss with a ‘precursor”.  Why not just ingest nitric oxide directly?  This is sometimes done to help premature infants in respiratory distress.  However, nitric oxide is also a highly reactive gas, and nitrogen oxides have long been recognized as toxic environmental pollutants.  The most common ways to increase your body’s nitric oxide are to 1) eat a diet full of  protein-rich meat and poultry as well as beets and leafy greens…  2) supplement with arginine.
 
Let’s finish our nitric oxide six-degrees-of-Kevin-Bacon… Power Defender, a supplement intended to defend against the worst after-effects of a night of drinking, contains L-arginine.  This key ingredient converts into nitric oxide which has many benefits.  These are most famously documented by the scientific team that won the 1998 Nobel Prize.
 
Happily, we’re launching Power Defender on Kickstarter soon!  Also, we’re running a contest right now with fun weekly prizes and Power Defender samples.  Hope you’ll take a look.
 
 
To your health and happiness… Cheers!
 
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